For calculating Hydrogen Bond
HBPLUS, which is distributed with LIGPLOT: http://www.biochem.ucl.ac.uk/bsm/ligplot/ligplot.html
There's also HBOND, which comes with the JOY package:
http://www-cryst.bioc.cam.ac.uk/~joy/
they are free, but they all need Academic License which I can't apply individually, has to apply by UMDNJ.
2004年9月15日
for example, I want to know the H-Bonds in protein 1a2p, I go to
http://bioportal.weizmann.ac.il/oca-bin/csu?PDB_ID=1a2p
I found there's four sheet strands for each chain.I click on "Strand 1" on "A sheet" (residue 96-99)
I'll go to this page
from this page, if there's a "+" sign under HB colume, I know there's a H-Bond.
2004年9月6日
Virtual Stock Simulation/Game/Practice
free
http://game.marketwatch.com/Home/default.asp
fee need
http://www.stocktrak.com/
2004年9月5日
for Taipei, Taiwan's Aerial image, I use
this one as whole taiwan
http://921farmers.cultureworld.org/image/TaiwanNo1.jpg
+
this one for more detail image
http://iws.csrsr.ncu.edu.tw:8080/JSP/CSRSR/homepage.jsp?UserId=guest
+
this one for very very detail image
http://addr.tcg.gov.tw/
http://www.globalsecurity.org/military/world/taiwan/taipei.htm
this one as black and white detail
2004年8月24日
2004年8月17日
use xslt to translate xml data, and use treeview to display it.
http://aspnet.4guysfromrolla.com/articles/051403-1.2.aspx
TreeView (@msdn)
2004年8月15日
2004年8月11日
XML sorting, paging, multilevel, etc.
http://www.screenbooks.net/jorr/js/
Creating a Pageable, Sortable DataGrid using ASP.NET
http://msdn.microsoft.com/library/default.asp?url=/library/en-us/dnaspp/html/aspnet-pageablesortable.asp
2004年8月5日
there are some web sites related to http://geneticassociationdb.nih.gov/
http://www-alis.tokyo.jst.go.jp/HOWDY/
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=snp
http://hgvbase.cgb.ki.se/ (can't get final result 04/08/05)
2004年8月4日
You must install the .NET Framework Redistributable Package version 1.1 prior to installing the .NET Framework SDK.
2004年8月3日
use
http://eutils.ncbi.nlm.nih.gov/entrez/eutils/soap/eutils.wsdl
to check pubmed data
ex:
Feasibility of simplifying balloon mitral valvuloplasty by obviating left-sided cardiac catheterization using on-line guidance with transesophageal echocardiography.
PMID: 12796174
1. use run_eSearch
db=pubmed
term=Feasibility+of+simplifying+balloon+mitral+valvuloplasty
field=titl
you'll get PMID: 12796174
http://eutils.ncbi.nlm.nih.gov/entrez/eutils/esearch.fcgi?db=pubmed&term=Feasibility+of+simplifying+balloon+mitral+valvuloplasty&field=titl
2.use run_eSummary
db=pubmedid=12796174
you'll get:
Feasibility of simplifying balloon mitral valvuloplasty by obviating left-sided cardiac catheterization using on-line guidance with transesophageal echocardiography.
http://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&id=12796174&retmode=xml
2004年7月27日
online microarray analysis tools
http://gepas.bioinfo.cnio.es/tools.html
microarray softwares
http://ihome.cuhk.edu.hk/~b400559/arraysoft.html
inorder to implement a Dr. Lee's version of
http://geneticassociationdb.nih.gov
use this to transfer access data to mysql
http://www.kitebird.com/articles/access-migrate.html
use this to search pubmed through soap interface (XML,wsdl)
http://eutils.ncbi.nlm.nih.gov/entrez/query/static/esearch_help.html
2004年7月22日
Use this to calculate ANOVA
http://lgsun.grc.nia.nih.gov/ANOVA/bin/login.cgi
http://bioinformatics.uams.edu/page/
Use this to translate gene identifier
http://discover.nci.nih.gov/matchminer/html/MatchMinerInteractiveLookup.jsp
Use EXCEL to add color to updowngene.txt and use this to get it in pathway (colored)
http://www.genome.ad.jp/kegg-bin/mk_point_multi_html
I'm thinking about use pathway data and microarray data to form an automatic functional genetic discoverer. (use the same algorithm I do for Dr. Gu)
2004年7月13日
for researcher M.S.Chang
these tools might help.
ex:
String http://string.embl.de/
input sequence, get "predict functional associations proteins/genes"
supported by microarray, textmining, Co-occurrence, etc.
IntAct http://www.ebi.ac.uk/intact/index.html
input gene, it will give you proteins interact with the given gene.
supported by Experiments.
InterDom
input sequence, it will give you putative domain interactions
for example, it will give you some domains which has complexes with domain in given sequence (derived from PDB), or has protein interactions with domain in given sequence (derived from DIP).
after visit Mackay memorial hospital (in Taiwan)
I done some research on Database of Interacting Proteins (DIP)
ex: I want to know what proteins interact with P53
enter P53 in NodeID or Name field in this page
you will get DIP nodes for p53 in human and mouse
(DIP:368N, DIP:369N, DIP:5978N, DIP:24202N, etc)
in each DIP node, you can click on the "graph" link at top right corner
you'll see what other proteins interact with P53.
it also provides links to related information in
PDB, NCBI, Prosite, Smart, InterPro databases.
another one similar to this